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What Retains The Skin Lifted And Firm? The World Of Collagen. PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin. PR-Set7-mediated monomethylation of histone H4 lysine 20 at specific genomic regions induces transcriptional repression. EZH1 mediates methylation on histone H3 lysine...

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